AlfalfaGEDB Alfalfa Gene Editing Database

M. sativa cultivar XinJiangDaYe / MS.gene043078

Query id Subject id identity % alignment length mismatches gap openings q. start q. end s. start s. end e-value bit score
MS.gene043078.t1 MTR_4g031910 73.077 234 46 2 1 222 1 229 1.90e-114 326
MS.gene043078.t1 MTR_4g032290 70.902 244 36 2 1 222 1 231 2.78e-111 318
MS.gene043078.t1 MTR_4g032620 58.442 231 87 1 1 222 1 231 2.40e-96 280
MS.gene043078.t1 MTR_8g036130 58.300 247 78 4 1 222 1 247 1.00e-90 267
MS.gene043078.t1 MTR_4g032260 80.892 157 30 0 1 157 1 157 6.92e-83 244
MS.gene043078.t1 MTR_3g065100 48.133 241 100 4 1 219 1 238 1.14e-63 198
MS.gene043078.t1 MTR_3g466980 45.133 226 110 3 1 222 1 216 1.33e-61 192
MS.gene043078.t1 MTR_2g035610 72.131 122 34 0 1 122 1 122 5.32e-51 161
MS.gene043078.t1 MTR_4g032270 57.664 137 43 2 94 222 2 131 4.82e-47 152
MS.gene043078.t1 MTR_5g075380 46.452 155 82 1 1 155 1 154 2.28e-45 149
MS.gene043078.t1 MTR_4g063790 44.805 154 85 0 1 154 1 154 3.96e-45 148
MS.gene043078.t1 MTR_3g466830 47.020 151 79 1 3 153 2 151 8.21e-45 147
MS.gene043078.t1 MTR_3g467080 42.949 156 89 0 1 156 1 156 6.23e-43 142
MS.gene043078.t1 MTR_3g031100 35.545 211 128 3 1 206 1 208 7.81e-41 139
MS.gene043078.t1 MTR_2g016210 39.548 177 106 1 1 176 1 177 1.42e-40 139
MS.gene043078.t1 MTR_5g047580 44.231 156 85 2 1 156 1 154 1.79e-40 136
MS.gene043078.t1 MTR_3g466890 44.079 152 84 1 3 154 2 152 2.29e-39 133
MS.gene043078.t1 MTR_1g077390 41.401 157 88 3 1 156 1 154 1.77e-38 131
MS.gene043078.t1 MTR_3g465410 44.444 126 70 0 29 154 1 126 4.91e-35 121
MS.gene043078.t1 MTR_1g077320 43.590 156 86 2 1 156 1 154 8.14e-35 121
MS.gene043078.t1 MTR_1g090783 39.610 154 91 2 3 156 2 153 1.44e-34 120
MS.gene043078.t1 MTR_7g011950 42.949 156 87 2 1 156 1 154 2.08e-34 120
MS.gene043078.t1 MTR_1g090710 38.312 154 94 1 1 154 1 153 1.19e-33 118
MS.gene043078.t1 MTR_4g028720 42.308 156 88 2 1 156 1 154 2.68e-33 117
MS.gene043078.t1 MTR_1g090697 40.000 150 88 2 1 150 1 148 4.17e-33 117
MS.gene043078.t1 MTR_1g077300 42.949 156 85 2 1 156 1 152 5.93e-33 117
MS.gene043078.t1 MTR_1g084950 42.949 156 87 2 1 156 1 154 1.66e-32 115
MS.gene043078.t1 MTR_4g028800 77.143 70 14 1 1 70 1 68 5.05e-32 112
MS.gene043078.t1 MTR_7g055800 52.137 117 28 2 1 117 1 89 9.27e-31 109
MS.gene043078.t1 MTR_3g031240 33.333 156 104 0 1 156 1 156 5.22e-30 110
MS.gene043078.t1 MTR_3g466900 39.837 123 73 1 32 154 2 123 6.54e-28 103
MS.gene043078.t1 MTR_7g055790 54.054 111 33 1 1 111 59 151 1.97e-27 102
MS.gene043078.t1 MTR_3g466930 37.398 123 76 1 32 154 2 123 1.67e-25 97.1
MS.gene043078.t1 MTR_2g035580 36.306 157 99 1 1 157 1 156 2.52e-25 97.4
MS.gene043078.t1 MTR_7g055940 50.943 106 24 2 1 106 1 78 2.91e-25 94.7
MS.gene043078.t1 MTR_7g106510 39.370 127 77 0 3 129 6 132 9.51e-25 101
MS.gene043078.t1 MTR_4g019670 39.370 127 77 0 3 129 6 132 3.50e-24 100
MS.gene043078.t1 MTR_3g093900 32.394 142 96 0 3 144 6 147 1.67e-22 95.5
MS.gene043078.t1 MTR_5g047560 35.032 157 82 4 1 156 1 138 3.23e-22 88.6
MS.gene043078.t1 MTR_2g035590 59.259 81 33 0 74 154 1 81 1.92e-19 80.1
MS.gene043078.t1 MTR_6g018920 35.398 113 66 4 1 107 1 112 1.79e-13 68.6
MS.gene043078.t1 MTR_6g005450 35.398 113 66 4 1 107 1 112 2.20e-13 68.6
MS.gene043078.t1 MTR_1g114730 32.743 113 69 3 1 107 1 112 4.36e-13 67.8
MS.gene043078.t1 MTR_4g084780 37.838 111 53 2 74 168 1 111 1.29e-11 60.8
MS.gene043078.t1 MTR_6g005440 36.283 113 65 4 1 107 1 112 3.36e-11 62.0
Query id Subject id identity % alignment length mismatches gap openings q. start q. end s. start s. end e-value bit score
MS.gene043078.t1 AT5G48670 53.896 154 70 1 1 154 1 153 1.96e-45 154
MS.gene043078.t1 AT1G65300 42.262 168 87 2 3 161 2 168 5.06e-41 141
MS.gene043078.t1 AT5G26630 42.439 205 107 2 1 195 1 204 1.14e-40 138
MS.gene043078.t1 AT1G65330 42.857 168 88 2 3 163 2 168 1.04e-39 138
MS.gene043078.t1 AT5G26650 42.763 152 86 1 5 156 3 153 2.29e-36 131
MS.gene043078.t1 AT5G27960 42.105 152 87 1 5 156 3 153 1.08e-35 128
MS.gene043078.t1 AT1G31630 36.905 168 97 3 3 163 2 167 4.15e-35 127
MS.gene043078.t1 AT1G31640 38.411 151 91 2 3 153 2 150 1.21e-31 120
MS.gene043078.t1 AT2G28700 36.158 177 108 2 1 175 1 174 4.25e-31 116
MS.gene043078.t1 AT5G27810 54.839 93 42 0 29 121 1 93 6.52e-31 110
MS.gene043078.t1 AT3G05860 36.076 158 100 1 1 158 1 157 1.85e-30 112
MS.gene043078.t1 AT3G05860 36.076 158 100 1 1 158 1 157 5.56e-30 112
MS.gene043078.t1 AT3G05860 36.076 158 100 1 1 158 1 157 6.73e-30 112
MS.gene043078.t1 AT1G22590 31.481 162 107 1 1 162 1 158 1.20e-25 98.2
MS.gene043078.t1 AT5G26580 35.065 154 85 2 1 154 1 139 6.24e-25 100
MS.gene043078.t1 AT5G06500 34.395 157 101 2 1 157 1 155 2.91e-21 89.0
MS.gene043078.t1 AT2G40210 35.802 162 101 2 1 162 1 159 1.51e-19 86.3
MS.gene043078.t1 AT5G58890 38.583 127 67 5 6 123 6 130 1.82e-16 76.6
MS.gene043078.t1 AT5G55690 42.308 78 38 2 1 71 1 78 1.72e-13 68.2
MS.gene043078.t1 AT5G55690 42.308 78 38 2 1 71 1 78 1.72e-13 68.2
MS.gene043078.t1 AT2G15660 30.088 113 74 2 38 150 31 138 3.16e-11 61.6

Find 61 sgRNAs with CRISPR-Local

Find 60 sgRNAs with CRISPR-GE


CRISPR-Local

CRISPR-Local
sgRNA_sequence on_target_score Position Region
ATCCTTCAAGGTAGTAAATT+AGG 0.161446 4.2:+73110055 None:intergenic
AGAAACAAAGAAAAGAAAAT+AGG 0.231520 4.2:-73110402 MS.gene043078:CDS
CCCTTTGGTGAGATCAATTC+TGG 0.238779 4.2:-73110085 MS.gene043078:CDS
GAGCGAAGAAATGGCAATTA+TGG 0.251384 4.2:-73110206 MS.gene043078:CDS
TACCAATGTCCTTCAAATTA+TGG 0.254451 4.2:+73110275 None:intergenic
AAGAAAGGGTCTATTGAAAA+AGG 0.312767 4.2:-73110635 MS.gene043078:CDS
ATCTCTGGCTGAGGCTCATA+AGG 0.350996 4.2:+73110559 None:intergenic
AAAATGTCATCACCATTAAT+AGG 0.355958 4.2:+73110163 None:intergenic
ATGAGCCTCAGCCAGAGATT+TGG 0.374512 4.2:-73110555 MS.gene043078:CDS
TTTGCAAAGTCAATTATTGA+TGG 0.379269 4.2:-73110143 MS.gene043078:CDS
GCCCTAATTTACTACCTTGA+AGG 0.380748 4.2:-73110057 None:intergenic
TCCTTCAAGGTAGTAAATTA+GGG 0.396741 4.2:+73110056 None:intergenic
GAAGGACATTGGTAGACGTT+TGG 0.410243 4.2:-73110266 MS.gene043078:CDS
TCTGGTGAAGGCCAAATCTC+TGG 0.413104 4.2:+73110544 None:intergenic
GAAACAAAGAAAAGAAAATA+GGG 0.419680 4.2:-73110401 MS.gene043078:CDS
AGCGAAGAAATGGCAATTAT+GGG 0.425600 4.2:-73110205 MS.gene043078:CDS
AGCATCTAGGAGCGAAGAAA+TGG 0.428793 4.2:-73110215 MS.gene043078:CDS
GTTGATTGACCATAATTTGA+AGG 0.445081 4.2:-73110284 MS.gene043078:CDS
GATGCTGCTGGAGGTGGTAG+TGG 0.453710 4.2:+73110232 None:intergenic
CTCCTAGATGCTGCTGGAGG+TGG 0.459401 4.2:+73110226 None:intergenic
CACAACCATGGCTAGAAGTA+AGG 0.461347 4.2:-73110713 None:intergenic
CTCATAAGGGCCATACACTA+TGG 0.468858 4.2:+73110573 None:intergenic
ATCATACAAGAAAAGAAGAA+AGG 0.473094 4.2:-73110650 MS.gene043078:CDS
CTTGACACAAAGGGTTCTGA+AGG 0.478789 4.2:-73110440 MS.gene043078:CDS
TCAATTATTGATGGACTCAA+TGG 0.482426 4.2:-73110134 MS.gene043078:CDS
TTGATTTGAGTTATCTTACT+TGG 0.482489 4.2:-73110306 MS.gene043078:CDS
CATGTTGGGATACCTATTAA+TGG 0.485702 4.2:-73110175 MS.gene043078:CDS
TCTTCGCTCCTAGATGCTGC+TGG 0.487238 4.2:+73110220 None:intergenic
TTATGGGTCATGGACATGTT+GGG 0.500968 4.2:-73110189 MS.gene043078:CDS
TGCGGCATCATTGACAATGA+AGG 0.507200 4.2:+73110681 None:intergenic
ATTATGGGTCATGGACATGT+TGG 0.516074 4.2:-73110190 MS.gene043078:CDS
AGAGACTTTCTTGACACAAA+GGG 0.517022 4.2:-73110449 MS.gene043078:CDS
GACCATAATTTGAAGGACAT+TGG 0.517963 4.2:-73110277 MS.gene043078:CDS
GAAATGGCAATTATGGGTCA+TGG 0.521926 4.2:-73110199 MS.gene043078:CDS
GGACATTGGTAGACGTTTGG+CGG 0.524285 4.2:-73110263 MS.gene043078:CDS
TTTGTGTCAAGAAAGTCTCT+TGG 0.525855 4.2:+73110452 None:intergenic
TCATACAAGAAAAGAAGAAA+GGG 0.526600 4.2:-73110649 MS.gene043078:CDS
TTTAACCTTACTTCTAGCCA+TGG 0.533701 4.2:+73110708 None:intergenic
TACCACCTCCAGCAGCATCT+AGG 0.540428 4.2:-73110228 MS.gene043078:CDS
ATATCTCATTGTCTCAATGA+AGG 0.546787 4.2:-73110358 MS.gene043078:CDS
CCAGAATTGATCTCACCAAA+GGG 0.554343 4.2:+73110085 None:intergenic
GTGCAAGAGACAGTGCCCTT+TGG 0.557727 4.2:-73110100 MS.gene043078:CDS
GAAGCCTGTGCCATAGTGTA+TGG 0.559714 4.2:-73110583 MS.gene043078:CDS
GAAGGCCAAATCTCTGGCTG+AGG 0.560020 4.2:+73110550 None:intergenic
TCTCTGGCTGAGGCTCATAA+GGG 0.571102 4.2:+73110560 None:intergenic
GAGATTTGGCCTTCACCAGA+GGG 0.580805 4.2:-73110541 MS.gene043078:CDS
TCCAGAATTGATCTCACCAA+AGG 0.590517 4.2:+73110084 None:intergenic
ACAGGCTTCAATGCCACAGA+GGG 0.601811 4.2:+73110597 None:intergenic
GATTTGGCCTTCACCAGAGG+GGG 0.601928 4.2:-73110539 MS.gene043078:CDS
CTTGTATGATTCTTTCCTTG+CGG 0.605657 4.2:+73110663 None:intergenic
TTGATGGACTCAATGGTGGC+TGG 0.607204 4.2:-73110127 MS.gene043078:CDS
AAGAGACTTTCTTGACACAA+AGG 0.607804 4.2:-73110450 MS.gene043078:CDS
AGAGATTTGGCCTTCACCAG+AGG 0.617598 4.2:-73110542 MS.gene043078:CDS
AGGGCCATACACTATGGCAC+AGG 0.641363 4.2:+73110579 None:intergenic
TCATTGTCAATGATGCCGCA+AGG 0.664783 4.2:-73110678 MS.gene043078:CDS
ATTATTGATGGACTCAATGG+TGG 0.666274 4.2:-73110131 MS.gene043078:CDS
TCGCTCCTAGATGCTGCTGG+AGG 0.676090 4.2:+73110223 None:intergenic
GCTGAACTTAGCACCCTCTG+TGG 0.677042 4.2:-73110610 MS.gene043078:CDS
TGTGCACGACAATATGTCAA+CGG 0.688304 4.2:-73110329 MS.gene043078:CDS
CACAGGCTTCAATGCCACAG+AGG 0.696692 4.2:+73110596 None:intergenic
AGATTTGGCCTTCACCAGAG+GGG 0.703414 4.2:-73110540 MS.gene043078:CDS

CRISPR-GE

badsite warning sgRNA_sequence Strand Position Region GC_content
!! AGAAACAAAGAAAAGAAAAT+AGG - chr4.2:73110364-73110383 MS.gene043078:CDS 20.0%
!! GAAACAAAGAAAAGAAAATA+GGG - chr4.2:73110365-73110384 MS.gene043078:CDS 20.0%
! AAAATGTCATCACCATTAAT+AGG + chr4.2:73110606-73110625 None:intergenic 25.0%
! ATCATACAAGAAAAGAAGAA+AGG - chr4.2:73110116-73110135 MS.gene043078:CDS 25.0%
! TCATACAAGAAAAGAAGAAA+GGG - chr4.2:73110117-73110136 MS.gene043078:CDS 25.0%
! TTTGCAAAGTCAATTATTGA+TGG - chr4.2:73110623-73110642 MS.gene043078:CDS 25.0%
!! TTGATTTGAGTTATCTTACT+TGG - chr4.2:73110460-73110479 MS.gene043078:CDS 25.0%
AAGAAAGGGTCTATTGAAAA+AGG - chr4.2:73110131-73110150 MS.gene043078:CDS 30.0%
ATATCTCATTGTCTCAATGA+AGG - chr4.2:73110408-73110427 MS.gene043078:CDS 30.0%
GTTGATTGACCATAATTTGA+AGG - chr4.2:73110482-73110501 MS.gene043078:CDS 30.0%
TACCAATGTCCTTCAAATTA+TGG + chr4.2:73110494-73110513 None:intergenic 30.0%
!! TCAATTATTGATGGACTCAA+TGG - chr4.2:73110632-73110651 MS.gene043078:CDS 30.0%
AAGAGACTTTCTTGACACAA+AGG - chr4.2:73110316-73110335 MS.gene043078:CDS 35.0%
AGAGACTTTCTTGACACAAA+GGG - chr4.2:73110317-73110336 MS.gene043078:CDS 35.0%
AGCGAAGAAATGGCAATTAT+GGG - chr4.2:73110561-73110580 MS.gene043078:CDS 35.0%
CATGTTGGGATACCTATTAA+TGG - chr4.2:73110591-73110610 MS.gene043078:CDS 35.0%
CTTGTATGATTCTTTCCTTG+CGG + chr4.2:73110106-73110125 None:intergenic 35.0%
GACCATAATTTGAAGGACAT+TGG - chr4.2:73110489-73110508 MS.gene043078:CDS 35.0%
TTTGTGTCAAGAAAGTCTCT+TGG + chr4.2:73110317-73110336 None:intergenic 35.0%
!! ATTATTGATGGACTCAATGG+TGG - chr4.2:73110635-73110654 MS.gene043078:CDS 35.0%
ATTATGGGTCATGGACATGT+TGG - chr4.2:73110576-73110595 MS.gene043078:CDS 40.0%
CCAGAATTGATCTCACCAAA+GGG + chr4.2:73110684-73110703 None:intergenic 40.0%
GAAATGGCAATTATGGGTCA+TGG - chr4.2:73110567-73110586 MS.gene043078:CDS 40.0%
GAGCGAAGAAATGGCAATTA+TGG - chr4.2:73110560-73110579 MS.gene043078:CDS 40.0%
TCCAGAATTGATCTCACCAA+AGG + chr4.2:73110685-73110704 None:intergenic 40.0%
TGTGCACGACAATATGTCAA+CGG - chr4.2:73110437-73110456 MS.gene043078:CDS 40.0%
TTATGGGTCATGGACATGTT+GGG - chr4.2:73110577-73110596 MS.gene043078:CDS 40.0%
!! CGTCATGAATTTTGAGAGCA+CGG + chr4.2:73110259-73110278 None:intergenic 40.0%
!! TGAATTTTGAGAGCACGGAT+TGG + chr4.2:73110254-73110273 None:intergenic 40.0%
AGCATCTAGGAGCGAAGAAA+TGG - chr4.2:73110551-73110570 MS.gene043078:CDS 45.0%
CCCTTTGGTGAGATCAATTC+TGG - chr4.2:73110681-73110700 MS.gene043078:CDS 45.0%
CTCATAAGGGCCATACACTA+TGG + chr4.2:73110196-73110215 None:intergenic 45.0%
GAAGGACATTGGTAGACGTT+TGG - chr4.2:73110500-73110519 MS.gene043078:CDS 45.0%
TCATTGTCAATGATGCCGCA+AGG - chr4.2:73110088-73110107 MS.gene043078:CDS 45.0%
TGCGGCATCATTGACAATGA+AGG + chr4.2:73110088-73110107 None:intergenic 45.0%
! CTTGACACAAAGGGTTCTGA+AGG - chr4.2:73110326-73110345 MS.gene043078:CDS 45.0%
ACAGGCTTCAATGCCACAGA+GGG + chr4.2:73110172-73110191 None:intergenic 50.0%
ATCTCTGGCTGAGGCTCATA+AGG + chr4.2:73110210-73110229 None:intergenic 50.0%
ATGAGCCTCAGCCAGAGATT+TGG - chr4.2:73110211-73110230 MS.gene043078:CDS 50.0%
GAAGCCTGTGCCATAGTGTA+TGG - chr4.2:73110183-73110202 MS.gene043078:CDS 50.0%
GGACATTGGTAGACGTTTGG+CGG - chr4.2:73110503-73110522 MS.gene043078:CDS 50.0%
TCTCTGGCTGAGGCTCATAA+GGG + chr4.2:73110209-73110228 None:intergenic 50.0%
TCTGGTGAAGGCCAAATCTC+TGG + chr4.2:73110225-73110244 None:intergenic 50.0%
! AGAGATTTGGCCTTCACCAG+AGG - chr4.2:73110224-73110243 MS.gene043078:CDS 50.0%
! AGATTTGGCCTTCACCAGAG+GGG - chr4.2:73110226-73110245 MS.gene043078:CDS 50.0%
! GAGATTTGGCCTTCACCAGA+GGG - chr4.2:73110225-73110244 MS.gene043078:CDS 50.0%
!! TTGATGGACTCAATGGTGGC+TGG - chr4.2:73110639-73110658 MS.gene043078:CDS 50.0%
AGGGCCATACACTATGGCAC+AGG + chr4.2:73110190-73110209 None:intergenic 55.0%
CACAGGCTTCAATGCCACAG+AGG + chr4.2:73110173-73110192 None:intergenic 55.0%
GAAGGCCAAATCTCTGGCTG+AGG + chr4.2:73110219-73110238 None:intergenic 55.0%
GCTGAACTTAGCACCCTCTG+TGG - chr4.2:73110156-73110175 MS.gene043078:CDS 55.0%
GTGCAAGAGACAGTGCCCTT+TGG - chr4.2:73110666-73110685 MS.gene043078:CDS 55.0%
TACCACCTCCAGCAGCATCT+AGG - chr4.2:73110538-73110557 MS.gene043078:CDS 55.0%
TCTTCGCTCCTAGATGCTGC+TGG + chr4.2:73110549-73110568 None:intergenic 55.0%
! GATTTGGCCTTCACCAGAGG+GGG - chr4.2:73110227-73110246 MS.gene043078:CDS 55.0%
CTCCTAGATGCTGCTGGAGG+TGG + chr4.2:73110543-73110562 None:intergenic 60.0%
GATGCTGCTGGAGGTGGTAG+TGG + chr4.2:73110537-73110556 None:intergenic 60.0%
GATTGGACCCCCTCTGGTGA+AGG + chr4.2:73110237-73110256 None:intergenic 60.0%
TCGCTCCTAGATGCTGCTGG+AGG + chr4.2:73110546-73110565 None:intergenic 60.0%
!! AGCACGGATTGGACCCCCTC+TGG + chr4.2:73110243-73110262 None:intergenic 65.0%


Chromosome Type Strat End Strand Name
chr4.2 gene 73110060 73110728 73110060 ID=MS.gene043078
chr4.2 mRNA 73110060 73110728 73110060 ID=MS.gene043078.t1;Parent=MS.gene043078
chr4.2 exon 73110060 73110728 73110060 ID=MS.gene043078.t1.exon1;Parent=MS.gene043078.t1
chr4.2 CDS 73110060 73110728 73110060 ID=cds.MS.gene043078.t1;Parent=MS.gene043078.t1
Gene Sequence

>MS.gene043078

ATGGCTAGAAGTAAGGTTAAACTTGCCTTCATTGTCAATGATGCCGCAAGGAAAGAATCATACAAGAAAAGAAGAAAGGGTCTATTGAAAAAGGTTGCTGAACTTAGCACCCTCTGTGGCATTGAAGCCTGTGCCATAGTGTATGGCCCTTATGAGCCTCAGCCAGAGATTTGGCCTTCACCAGAGGGGGTCCAATCCGTGCTCTCAAAATTCATGACGATGCACGAGTTTCAAAAGTGCAAGAAAATGATGAACCAAGAGACTTTCTTGACACAAAGGGTTCTGAAGGCTGAAGAGAAATTGAAGAAACAAAGAAAAGAAAATAGGGAGCAAGAGATGACAATACTCATATCTCATTGTCTCAATGAAGGTAGAGTTGTGCACGACAATATGTCAACGGTTGATTTGAGTTATCTTACTTGGTTGATTGACCATAATTTGAAGGACATTGGTAGACGTTTGGCGGCAACAGTGCCACTACCACCTCCAGCAGCATCTAGGAGCGAAGAAATGGCAATTATGGGTCATGGACATGTTGGGATACCTATTAATGGTGATGACATTTTGCAAAGTCAATTATTGATGGACTCAATGGTGGCTGGTAATGTGCAAGAGACAGTGCCCTTTGGTGAGATCAATTCTGGAGTTTGCCCTAATTTACTACCTTGA
Protein sequence

>MS.gene043078.t1

MARSKVKLAFIVNDAARKESYKKRRKGLLKKVAELSTLCGIEACAIVYGPYEPQPEIWPSPEGVQSVLSKFMTMHEFQKCKKMMNQETFLTQRVLKAEEKLKKQRKENREQEMTILISHCLNEGRVVHDNMSTVDLSYLTWLIDHNLKDIGRRLAATVPLPPPAASRSEEMAIMGHGHVGIPINGDDILQSQLLMDSMVAGNVQETVPFGEINSGVCPNLLP