AlfalfaGEDB Alfalfa Gene Editing Database

M. sativa cultivar XinJiangDaYe / MS.gene88150

Query id Subject id identity % alignment length mismatches gap openings q. start q. end s. start s. end e-value bit score
MS.gene88150.t1 MTR_4g031910 71.795 234 49 2 1 222 1 229 1.59e-112 322
MS.gene88150.t1 MTR_4g032290 68.443 244 42 2 1 222 1 231 1.68e-108 311
MS.gene88150.t1 MTR_4g032620 58.009 231 88 1 1 222 1 231 6.34e-94 274
MS.gene88150.t1 MTR_8g036130 56.680 247 82 4 1 222 1 247 2.59e-88 261
MS.gene88150.t1 MTR_4g032260 78.981 157 33 0 1 157 1 157 4.10e-79 234
MS.gene88150.t1 MTR_3g065100 48.963 241 98 4 1 219 1 238 8.14e-65 201
MS.gene88150.t1 MTR_3g466980 45.690 232 101 5 1 218 1 221 1.82e-64 199
MS.gene88150.t1 MTR_2g035610 71.311 122 35 0 1 122 1 122 1.72e-50 160
MS.gene88150.t1 MTR_5g075380 47.742 155 80 1 1 155 1 154 2.80e-45 148
MS.gene88150.t1 MTR_3g466830 48.344 151 77 1 3 153 2 151 3.64e-45 148
MS.gene88150.t1 MTR_4g063790 44.805 154 85 0 1 154 1 154 1.57e-44 147
MS.gene88150.t1 MTR_4g032270 72.917 96 18 1 135 222 36 131 2.82e-44 145
MS.gene88150.t1 MTR_3g031100 34.821 224 134 4 1 219 1 217 3.96e-43 145
MS.gene88150.t1 MTR_3g467080 42.949 156 89 0 1 156 1 156 1.78e-42 141
MS.gene88150.t1 MTR_2g016210 39.011 182 109 2 1 180 1 182 2.11e-40 138
MS.gene88150.t1 MTR_3g466890 45.395 152 82 1 3 154 2 152 4.06e-40 135
MS.gene88150.t1 MTR_5g047580 45.513 156 83 2 1 156 1 154 4.44e-40 135
MS.gene88150.t1 MTR_1g077390 41.667 156 89 2 1 156 1 154 1.48e-36 126
MS.gene88150.t1 MTR_1g090783 41.558 154 88 2 3 156 2 153 1.86e-35 123
MS.gene88150.t1 MTR_3g465410 43.651 126 71 0 29 154 1 126 4.64e-34 119
MS.gene88150.t1 MTR_1g077320 43.590 156 86 2 1 156 1 154 6.39e-34 119
MS.gene88150.t1 MTR_1g090710 38.961 154 93 1 1 154 1 153 7.25e-34 119
MS.gene88150.t1 MTR_7g011950 42.949 156 87 2 1 156 1 154 1.33e-33 118
MS.gene88150.t1 MTR_4g028720 43.590 156 86 2 1 156 1 154 1.69e-33 118
MS.gene88150.t1 MTR_1g084950 44.231 156 85 2 1 156 1 154 8.40e-33 116
MS.gene88150.t1 MTR_1g090697 40.000 150 88 2 1 150 1 148 1.07e-31 113
MS.gene88150.t1 MTR_1g077300 42.949 156 85 2 1 156 1 152 2.28e-31 112
MS.gene88150.t1 MTR_4g028800 77.143 70 14 1 1 70 1 68 3.69e-31 109
MS.gene88150.t1 MTR_3g031240 33.974 156 103 0 1 156 1 156 1.54e-30 111
MS.gene88150.t1 MTR_7g055800 49.573 117 31 2 1 117 1 89 1.32e-28 103
MS.gene88150.t1 MTR_3g466900 40.650 123 72 1 32 154 2 123 4.49e-28 103
MS.gene88150.t1 MTR_7g055790 52.252 111 35 1 1 111 59 151 7.58e-26 98.6
MS.gene88150.t1 MTR_2g035580 38.217 157 96 1 1 157 1 156 1.09e-25 98.2
MS.gene88150.t1 MTR_3g466930 38.211 123 75 1 32 154 2 123 1.32e-25 97.4
MS.gene88150.t1 MTR_7g106510 39.370 127 77 0 3 129 6 132 5.54e-24 99.4
MS.gene88150.t1 MTR_4g019670 40.157 127 76 0 3 129 6 132 5.65e-24 99.4
MS.gene88150.t1 MTR_7g055940 49.057 106 26 2 1 106 1 78 1.03e-23 90.5
MS.gene88150.t1 MTR_5g047560 35.897 156 82 3 1 156 1 138 1.49e-22 89.7
MS.gene88150.t1 MTR_3g093900 31.690 142 97 0 3 144 6 147 1.99e-21 92.4
MS.gene88150.t1 MTR_2g035590 55.556 81 36 0 74 154 1 81 2.70e-17 74.7
MS.gene88150.t1 MTR_1g114730 31.858 113 70 3 1 107 1 112 3.60e-13 67.8
MS.gene88150.t1 MTR_6g018920 32.743 113 69 4 1 107 1 112 4.83e-13 67.4
MS.gene88150.t1 MTR_6g005450 33.628 113 68 4 1 107 1 112 3.18e-12 65.1
MS.gene88150.t1 MTR_6g005440 35.398 113 66 3 1 107 1 112 4.19e-11 61.6
MS.gene88150.t1 MTR_4g084780 37.838 111 53 2 74 168 1 111 6.73e-11 58.9
Query id Subject id identity % alignment length mismatches gap openings q. start q. end s. start s. end e-value bit score
MS.gene88150.t1 AT5G48670 55.195 154 68 1 1 154 1 153 1.58e-46 156
MS.gene88150.t1 AT1G65330 42.246 187 94 3 3 176 2 187 8.31e-41 140
MS.gene88150.t1 AT5G26630 44.503 191 95 2 1 181 1 190 2.32e-40 137
MS.gene88150.t1 AT1G65300 46.053 152 81 1 3 154 2 152 2.55e-40 139
MS.gene88150.t1 AT5G26650 40.476 168 89 2 5 162 3 169 1.21e-34 127
MS.gene88150.t1 AT5G27960 40.476 168 89 3 5 162 3 169 2.69e-34 125
MS.gene88150.t1 AT1G31630 36.905 168 95 3 3 161 2 167 2.21e-33 122
MS.gene88150.t1 AT1G31640 39.735 151 89 2 3 153 2 150 1.33e-31 120
MS.gene88150.t1 AT3G05860 37.975 158 97 1 1 158 1 157 1.10e-30 112
MS.gene88150.t1 AT3G05860 37.975 158 97 1 1 158 1 157 1.22e-30 113
MS.gene88150.t1 AT3G05860 37.975 158 97 1 1 158 1 157 1.53e-30 113
MS.gene88150.t1 AT2G28700 37.423 163 97 2 1 161 1 160 4.47e-30 114
MS.gene88150.t1 AT5G27810 54.839 93 42 0 29 121 1 93 5.94e-30 108
MS.gene88150.t1 AT1G22590 32.099 162 106 1 1 162 1 158 3.95e-26 99.8
MS.gene88150.t1 AT5G26580 34.416 154 86 2 1 154 1 139 7.58e-23 95.1
MS.gene88150.t1 AT5G06500 35.032 157 100 2 1 157 1 155 2.41e-22 91.7
MS.gene88150.t1 AT2G40210 37.984 129 79 1 1 129 1 128 1.45e-17 80.5
MS.gene88150.t1 AT5G58890 37.795 127 68 5 6 123 6 130 3.57e-15 73.2
MS.gene88150.t1 AT5G55690 42.308 78 38 2 1 71 1 78 2.78e-12 64.7
MS.gene88150.t1 AT5G55690 42.308 78 38 2 1 71 1 78 2.78e-12 64.7
MS.gene88150.t1 AT5G27944 33.333 108 61 2 24 130 41 138 7.28e-11 60.1
MS.gene88150.t1 AT5G27090 34.444 90 58 1 7 95 23 112 7.55e-11 59.7

Find 59 sgRNAs with CRISPR-Local

Find 61 sgRNAs with CRISPR-GE


CRISPR-Local

CRISPR-Local
sgRNA_sequence on_target_score Position Region
AGAAACAAAGAAAAGAAAAT+AGG 0.231520 4.3:-68950929 MS.gene88150:CDS
CCCTTTGGTGAGATCAATTA+TGG 0.234667 4.3:-68950612 MS.gene88150:CDS
TACCAATGTCCTTCAAATTA+TGG 0.254451 4.3:+68950802 None:intergenic
ATAATTTCATCATCATTAAT+AGG 0.285530 4.3:+68950690 None:intergenic
GTGAGATCAATTATGGAGTT+TGG 0.309548 4.3:-68950605 MS.gene88150:CDS
AACAAAGGGTCTATTGAAAA+AGG 0.314581 4.3:-68951162 MS.gene88150:CDS
ATGAGCCTCAACCTGAGATT+TGG 0.345571 4.3:-68951082 MS.gene88150:CDS
AACATCTAGGAGTGAGGAAA+TGG 0.347038 4.3:-68950742 MS.gene88150:CDS
ATCCTTCAAGGTAGTAAATC+AGG 0.372648 4.3:+68950582 None:intergenic
TATGCAAAGTCAATTATTGA+TGG 0.385590 4.3:-68950670 MS.gene88150:CDS
TCCTCACTCCTAGATGTTGT+TGG 0.401049 4.3:+68950747 None:intergenic
GAAGGACATTGGTAGACGTT+TGG 0.410243 4.3:-68950793 MS.gene88150:CDS
GAAACAAAGAAAAGAAAATA+GGG 0.419680 4.3:-68950928 MS.gene88150:CDS
GGCCTGATTTACTACCTTGA+AGG 0.422090 4.3:-68950584 None:intergenic
AGTGAGGAAATGGGAATTGT+GGG 0.443118 4.3:-68950732 MS.gene88150:CDS
GCTGAACTTAGCACCCTTTG+TGG 0.444195 4.3:-68951137 MS.gene88150:CDS
CTAGATGTTGTTGGAGGTGG+TGG 0.444811 4.3:+68950756 None:intergenic
GTTGATTGACCATAATTTGA+AGG 0.445081 4.3:-68950811 MS.gene88150:CDS
TTGTGGGTCATGGCCATGTT+GGG 0.452922 4.3:-68950716 MS.gene88150:CDS
CACAACCATGGCTAGAAGTA+AGG 0.457305 4.3:-68951240 None:intergenic
CTCCTAGATGTTGTTGGAGG+TGG 0.461559 4.3:+68950753 None:intergenic
TCTGGTGAAGGCCAAATCTC+AGG 0.467267 4.3:+68951071 None:intergenic
CTCATAAGAGCCATACACTA+TGG 0.467809 4.3:+68951100 None:intergenic
ATTGTGGGTCATGGCCATGT+TGG 0.468248 4.3:-68950717 MS.gene88150:CDS
TCAATTATTGATGGACTCAA+TGG 0.482426 4.3:-68950661 MS.gene88150:CDS
TTGATTTGAGTTATCTTACT+TGG 0.482489 4.3:-68950833 MS.gene88150:CDS
CTTGACACAAAGGATTCTGA+AGG 0.491635 4.3:-68950967 MS.gene88150:CDS
TGCAGCATCATTGACAATGA+AGG 0.502295 4.3:+68951208 None:intergenic
GATGTTGTTGGAGGTGGTGG+TGG 0.505459 4.3:+68950759 None:intergenic
TCACTCCTAGATGTTGTTGG+AGG 0.510768 4.3:+68950750 None:intergenic
TTTGTGTCAAGAAAGTCTCT+TGG 0.512375 4.3:+68950979 None:intergenic
GAGTGAGGAAATGGGAATTG+TGG 0.516317 4.3:-68950733 MS.gene88150:CDS
GACCATAATTTGAAGGACAT+TGG 0.517963 4.3:-68950804 MS.gene88150:CDS
GGACATTGGTAGACGTTTGG+CGG 0.524285 4.3:-68950790 MS.gene88150:CDS
ACATCTAGGAGTGAGGAAAT+GGG 0.532509 4.3:-68950741 MS.gene88150:CDS
CACCACCTCCAACAACATCT+AGG 0.540352 4.3:-68950755 MS.gene88150:CDS
ATGTCTCATTGTCTCAATGA+AGG 0.542205 4.3:-68950885 MS.gene88150:CDS
ACAGGCTTCAATGCCACAAA+GGG 0.554817 4.3:+68951124 None:intergenic
CCATAATTGATCTCACCAAA+GGG 0.558369 4.3:+68950612 None:intergenic
GAAGCCTGTGCCATAGTGTA+TGG 0.560968 4.3:-68951110 MS.gene88150:CDS
GAGATTTGGCCTTCACCAGA+GGG 0.565461 4.3:-68951068 MS.gene88150:CDS
TTTAACCTTACTTCTAGCCA+TGG 0.572129 4.3:+68951235 None:intergenic
GATTTGGCCTTCACCAGAGG+GGG 0.573799 4.3:-68951066 MS.gene88150:CDS
TCCATAATTGATCTCACCAA+AGG 0.580970 4.3:+68950611 None:intergenic
GTGCACGAGACAGTGCCCTT+TGG 0.582311 4.3:-68950627 MS.gene88150:CDS
CACAGGCTTCAATGCCACAA+AGG 0.583021 4.3:+68951123 None:intergenic
AAGAGACTTTCTTGACACAA+AGG 0.587821 4.3:-68950977 MS.gene88150:CDS
CATTAATAGGTATCCCAACA+TGG 0.589301 4.3:+68950703 None:intergenic
GAAGGCCAAATCTCAGGTTG+AGG 0.598100 4.3:+68951077 None:intergenic
ATTATTGATGGACTCAATGG+TGG 0.602430 4.3:-68950658 MS.gene88150:CDS
TGAGATTTGGCCTTCACCAG+AGG 0.614269 4.3:-68951069 MS.gene88150:CDS
GAAATGGGAATTGTGGGTCA+TGG 0.616732 4.3:-68950726 MS.gene88150:CDS
AGATTTGGCCTTCACCAGAG+GGG 0.650878 4.3:-68951067 MS.gene88150:CDS
TCCAACAACATCTAGGAGTG+AGG 0.651992 4.3:-68950748 MS.gene88150:CDS
TCATTGTCAATGATGCTGCA+AGG 0.652548 4.3:-68951205 MS.gene88150:CDS
AGAGCCATACACTATGGCAC+AGG 0.656790 4.3:+68951106 None:intergenic
TGTGCTCGACAATATGTCAA+CGG 0.675885 4.3:-68950856 MS.gene88150:CDS
TTATTGATGGACTCAATGGT+GGG 0.709058 4.3:-68950657 MS.gene88150:CDS
TTGATGGACTCAATGGTGGG+TGG 0.734497 4.3:-68950654 MS.gene88150:CDS

CRISPR-GE

badsite warning sgRNA_sequence Strand Position Region GC_content
!! ATAATTTCATCATCATTAAT+AGG + chr4.3:68951133-68951152 None:intergenic 15.0%
!! AACATACAAAAAAAGAACAA+AGG - chr4.3:68950643-68950662 MS.gene88150:CDS 20.0%
!! ACATACAAAAAAAGAACAAA+GGG - chr4.3:68950644-68950663 MS.gene88150:CDS 20.0%
!! AGAAACAAAGAAAAGAAAAT+AGG - chr4.3:68950891-68950910 MS.gene88150:CDS 20.0%
!! GAAACAAAGAAAAGAAAATA+GGG - chr4.3:68950892-68950911 MS.gene88150:CDS 20.0%
! TATGCAAAGTCAATTATTGA+TGG - chr4.3:68951150-68951169 MS.gene88150:CDS 25.0%
!! TTGATTTGAGTTATCTTACT+TGG - chr4.3:68950987-68951006 MS.gene88150:CDS 25.0%
AACAAAGGGTCTATTGAAAA+AGG - chr4.3:68950658-68950677 MS.gene88150:CDS 30.0%
GTTGATTGACCATAATTTGA+AGG - chr4.3:68951009-68951028 MS.gene88150:CDS 30.0%
TACCAATGTCCTTCAAATTA+TGG + chr4.3:68951021-68951040 None:intergenic 30.0%
!! TCAATTATTGATGGACTCAA+TGG - chr4.3:68951159-68951178 MS.gene88150:CDS 30.0%
AAGAGACTTTCTTGACACAA+AGG - chr4.3:68950843-68950862 MS.gene88150:CDS 35.0%
ATGTCTCATTGTCTCAATGA+AGG - chr4.3:68950935-68950954 MS.gene88150:CDS 35.0%
CATTAATAGGTATCCCAACA+TGG + chr4.3:68951120-68951139 None:intergenic 35.0%
CCATAATTGATCTCACCAAA+GGG + chr4.3:68951211-68951230 None:intergenic 35.0%
GACCATAATTTGAAGGACAT+TGG - chr4.3:68951016-68951035 MS.gene88150:CDS 35.0%
GTGAGATCAATTATGGAGTT+TGG - chr4.3:68951215-68951234 MS.gene88150:CDS 35.0%
TCCATAATTGATCTCACCAA+AGG + chr4.3:68951212-68951231 None:intergenic 35.0%
TTTGTGTCAAGAAAGTCTCT+TGG + chr4.3:68950844-68950863 None:intergenic 35.0%
!! ATTATTGATGGACTCAATGG+TGG - chr4.3:68951162-68951181 MS.gene88150:CDS 35.0%
!! TTATTGATGGACTCAATGGT+GGG - chr4.3:68951163-68951182 MS.gene88150:CDS 35.0%
AACATCTAGGAGTGAGGAAA+TGG - chr4.3:68951078-68951097 MS.gene88150:CDS 40.0%
ACATCTAGGAGTGAGGAAAT+GGG - chr4.3:68951079-68951098 MS.gene88150:CDS 40.0%
AGTGAGGAAATGGGAATTGT+GGG - chr4.3:68951088-68951107 MS.gene88150:CDS 40.0%
CCCTTTGGTGAGATCAATTA+TGG - chr4.3:68951208-68951227 MS.gene88150:CDS 40.0%
CTCATAAGAGCCATACACTA+TGG + chr4.3:68950723-68950742 None:intergenic 40.0%
CTTGACACAAAGGATTCTGA+AGG - chr4.3:68950853-68950872 MS.gene88150:CDS 40.0%
TCATTGTCAATGATGCTGCA+AGG - chr4.3:68950615-68950634 MS.gene88150:CDS 40.0%
TGCAGCATCATTGACAATGA+AGG + chr4.3:68950615-68950634 None:intergenic 40.0%
TGTGCTCGACAATATGTCAA+CGG - chr4.3:68950964-68950983 MS.gene88150:CDS 40.0%
!! CGTCATGAATTTTGAGAGCA+CGG + chr4.3:68950786-68950805 None:intergenic 40.0%
!! TGAATTTTGAGAGCACGGAT+TGG + chr4.3:68950781-68950800 None:intergenic 40.0%
ACAGGCTTCAATGCCACAAA+GGG + chr4.3:68950699-68950718 None:intergenic 45.0%
ATGAGCCTCAACCTGAGATT+TGG - chr4.3:68950738-68950757 MS.gene88150:CDS 45.0%
GAAATGGGAATTGTGGGTCA+TGG - chr4.3:68951094-68951113 MS.gene88150:CDS 45.0%
GAAGGACATTGGTAGACGTT+TGG - chr4.3:68951027-68951046 MS.gene88150:CDS 45.0%
GAGTGAGGAAATGGGAATTG+TGG - chr4.3:68951087-68951106 MS.gene88150:CDS 45.0%
TCACTCCTAGATGTTGTTGG+AGG + chr4.3:68951073-68951092 None:intergenic 45.0%
TCCAACAACATCTAGGAGTG+AGG - chr4.3:68951072-68951091 MS.gene88150:CDS 45.0%
TCCTCACTCCTAGATGTTGT+TGG + chr4.3:68951076-68951095 None:intergenic 45.0%
AGAGCCATACACTATGGCAC+AGG + chr4.3:68950717-68950736 None:intergenic 50.0%
ATTGTGGGTCATGGCCATGT+TGG - chr4.3:68951103-68951122 MS.gene88150:CDS 50.0%
CACAGGCTTCAATGCCACAA+AGG + chr4.3:68950700-68950719 None:intergenic 50.0%
CACCACCTCCAACAACATCT+AGG - chr4.3:68951065-68951084 MS.gene88150:CDS 50.0%
CTAGATGTTGTTGGAGGTGG+TGG + chr4.3:68951067-68951086 None:intergenic 50.0%
CTCCTAGATGTTGTTGGAGG+TGG + chr4.3:68951070-68951089 None:intergenic 50.0%
GAAGCCTGTGCCATAGTGTA+TGG - chr4.3:68950710-68950729 MS.gene88150:CDS 50.0%
GCTGAACTTAGCACCCTTTG+TGG - chr4.3:68950683-68950702 MS.gene88150:CDS 50.0%
GGACATTGGTAGACGTTTGG+CGG - chr4.3:68951030-68951049 MS.gene88150:CDS 50.0%
TCTGGTGAAGGCCAAATCTC+AGG + chr4.3:68950752-68950771 None:intergenic 50.0%
TTGTGGGTCATGGCCATGTT+GGG - chr4.3:68951104-68951123 MS.gene88150:CDS 50.0%
! AGATTTGGCCTTCACCAGAG+GGG - chr4.3:68950753-68950772 MS.gene88150:CDS 50.0%
! GAAGGCCAAATCTCAGGTTG+AGG + chr4.3:68950746-68950765 None:intergenic 50.0%
! GAGATTTGGCCTTCACCAGA+GGG - chr4.3:68950752-68950771 MS.gene88150:CDS 50.0%
! TGAGATTTGGCCTTCACCAG+AGG - chr4.3:68950751-68950770 MS.gene88150:CDS 50.0%
!! TTGATGGACTCAATGGTGGG+TGG - chr4.3:68951166-68951185 MS.gene88150:CDS 50.0%
! GATGTTGTTGGAGGTGGTGG+TGG + chr4.3:68951064-68951083 None:intergenic 55.0%
! GATTTGGCCTTCACCAGAGG+GGG - chr4.3:68950754-68950773 MS.gene88150:CDS 55.0%
GATTGGACCCCCTCTGGTGA+AGG + chr4.3:68950764-68950783 None:intergenic 60.0%
GTGCACGAGACAGTGCCCTT+TGG - chr4.3:68951193-68951212 MS.gene88150:CDS 60.0%
!! AGCACGGATTGGACCCCCTC+TGG + chr4.3:68950770-68950789 None:intergenic 65.0%


Chromosome Type Strat End Strand Name
chr4.3 gene 68950587 68951255 68950587 ID=MS.gene88150
chr4.3 mRNA 68950587 68951255 68950587 ID=MS.gene88150.t1;Parent=MS.gene88150
chr4.3 exon 68950587 68951255 68950587 ID=MS.gene88150.t1.exon1;Parent=MS.gene88150.t1
chr4.3 CDS 68950587 68951255 68950587 ID=cds.MS.gene88150.t1;Parent=MS.gene88150.t1
Gene Sequence

>MS.gene88150

ATGGCTAGAAGTAAGGTTAAACTCGCCTTCATTGTCAATGATGCTGCAAGGAAAGCAACATACAAAAAAAGAACAAAGGGTCTATTGAAAAAGGTTGCTGAACTTAGCACCCTTTGTGGCATTGAAGCCTGTGCCATAGTGTATGGCTCTTATGAGCCTCAACCTGAGATTTGGCCTTCACCAGAGGGGGTCCAATCCGTGCTCTCAAAATTCATGACGATGCACGAGTTTCAAAAGTGCAAGAAAATGCTGAACCAAGAGACTTTCTTGACACAAAGGATTCTGAAGGCTGAAGAGAAATTGAAGAAACAAAGAAAAGAAAATAGGGAGCAAGATATGACAATACTCATGTCTCATTGTCTCAATGAAGGTAGAGTTGTGCTCGACAATATGTCAACGGTTGATTTGAGTTATCTTACTTGGTTGATTGACCATAATTTGAAGGACATTGGTAGACGTTTGGCGGCAACAGTGCCACCACCACCTCCAACAACATCTAGGAGTGAGGAAATGGGAATTGTGGGTCATGGCCATGTTGGGATACCTATTAATGATGATGAAATTATGCAAAGTCAATTATTGATGGACTCAATGGTGGGTGGTAATGTGCACGAGACAGTGCCCTTTGGTGAGATCAATTATGGAGTTTGGCCTGATTTACTACCTTGA
Protein sequence

>MS.gene88150.t1

MARSKVKLAFIVNDAARKATYKKRTKGLLKKVAELSTLCGIEACAIVYGSYEPQPEIWPSPEGVQSVLSKFMTMHEFQKCKKMLNQETFLTQRILKAEEKLKKQRKENREQDMTILMSHCLNEGRVVLDNMSTVDLSYLTWLIDHNLKDIGRRLAATVPPPPPTTSRSEEMGIVGHGHVGIPINDDEIMQSQLLMDSMVGGNVHETVPFGEINYGVWPDLLP